Acute attacks
Sudden attacks of hereditary angioedema.
Clinical trials
Studies that evaluate the effectiveness and safety of medications or medical devices before they are approved for use by the general public.
Ecallantide (e-KAL-lan-tide)
A protein made in yeast cells; ecallantide is the active ingredient in KALBITOR (ecallantide).
HAE
Abbreviation for hereditary angioedema.
Hereditary Angioedema
A rare, hereditary disease of the immune system that causes attacks of sudden swelling in various parts of the body.
KALBITOR Access®
KALBITOR Access is a program that provides support services to hereditary angioedema patients, healthcare professionals and caregivers. KALBITOR Access services include health insurance coordination, financial assistance for qualified patients, and treatment location set up.
KALBITOR Care®
KALBITOR Care is a program offered by Dyax Corp. that provides comprehensive support services for KALBITOR patients. Available 24 hours a day, 7 days a week, KALBITOR Care offers a complete array of patient services and resources, along with the support of healthcare professionals.
KALBITOR Home Infusion Services®
KALBITOR Home Infusion Services is a program in which an experienced infusion nurse will administer your subcutaneous KALBITOR treatment in the comfort of your own home. This professional service is available to HAE patients, 16 years of age or older, who use KALBITOR to treat their sudden HAE attacks on demand. KALBITOR Home Infusion Services is not appropriate for treating laryngeal attacks.
KALBITOR® (KAL-bit-or)
A prescription medicine used to treat sudden attacks of hereditary angioedema in patients 12 years of age and older. KALBITOR® is not a cure for HAE.
Laryngeal attack
An HAE attack that affects the larynx (throat); this can block or close the airway, leading to difficulty breathing and, potentially, death.
Larynx
The part of the throat that contains the vocal cords and is used for breathing, swallowing, and talking.
On-demand treatment
On-demand HAE treatment is used to treat sudden attacks of HAE as they occur, in order to relieve symptoms associated with the attack. On-demand treatment is not used to prevent attacks from occurring.
Plasma kallikrein (kal'i-kre'in)
A protein in the body that triggers the release of a substance that may lead to hereditary angioedema attack symptoms.
Subcutaneous
Under the skin.
Trigger
In hereditary angioedema, something that causes an attack.
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You Are Not Alone

KALBITOR Care® offers tools and resources that make it easy for you to stay connected to the hereditary angioedema (HAE) community and keep on top of the newest information about HAE and treatments.

Please see Full Prescribing Information, including Boxed Warning and Medication Guide

Events

Meet Other Patients at a Local HAE Connect® Event

When living with hereditary angioedema (HAE), it's important to remember that you are not alone. That's why Dyax Corp. sponsors a series of FREE community programs in cities around the country.

These local gatherings allow HAE patients to connect with other patients in the area, as well as HAE experts. Share support and discuss what has helped you better manage your life with this disease. Watch the videos below to learn how other HAE patients have benefitted from connecting with peers, and find an event near you.

Watch Patients Reflect on the Importance of Connecting to Others with HAE

"I can share what I've gone through and what's worked for me. It makes you a stronger person." - Bob

 

"I learned a lot more about the disease, and even about myself." - Nicole

 

"The most positive thing I've brought out of the meetings is that you don't have to be alone." - Dave

 
 

 

Upcoming Events

Please see the schedule to register for your free local event. New events are being scheduled throughout the year, so if one is not currently planned for your area, please check back soon.

Dallas, TX

Date: Thursday, April 24, 2014

Program: On-Demand Treatment Plan for Sudden Attacks of HAE: Services and Options

Time: 6:00pm

Speaker: William Lumry, MD; University of Texas Southwestern Medical School; Director AARA Research Center in Dallas, TX

Venue: Perry's Steakhouse & Grille directions

Address: 2000 McKinney Avenue

            Dallas, TX 75201

Meeting Detail: Complimentary dinner event

RSVP: Phone: 617-894-2761 Eric Perry
         Online: Event RSVP

RSVP Deadline: April 22, 2014

Raleigh, NC

Date: Thursday, April 24, 2014

Program: On-Demand Treatment Plan for Sudden Attacks of HAE: Services and Options

Time: 6:30pm

Speaker: Jay Kashkin, MD; Allergy, Asthma and Immunology; Fairlawn, NJ

Venue: Ruth's Chris Steak House directions

Address: 4381 Lassiter Mill Road

            Raleigh, NC 27609

Meeting Detail: Complimentary dinner event; dress code is casual

RSVP: Phone: 704-576-4524 Julie Yencer
         Online: Event RSVP

RSVP Deadline: April 22, 2014

Salt Lake City, UT

Date: Friday, April 25, 2014

Program: On-Demand Treatment Plan for Sudden Attacks of HAE: Services and Options

Time: 6:30pm

Speaker: Douglas Jones, MD; Rocky Mountain Allergy, Asthma and Immunology

Venue: Buca di Beppo directions

Address: 202 West 300 South

            Salt Lake City, UT 84101

Meeting Detail: Complimentary dinner event

RSVP: Phone: 617-513-1582 Gwen Dafnis
         Online: Event RSVP

RSVP Deadline: April 23, 2014

Tampa, FL

Date: Tuesday, April 29, 2014

Program: On-Demand Treatment Plan for Sudden Attacks of HAE: Services and Options

Time: 6:30pm

Speaker: Mark Glaum, MD; Professor of Medicine; Department of Allergy and Immunology; University of South Florida School of Medicine

Venue: Fleming's Prime Steakhouse & Wine Bar directions

Address: 4322 West Boy Scout Boulevard

            Tampa, FL 33607

Meeting Detail: Complimentary dinner event

RSVP: Phone: 617-947-4067 Andrew Sternfield
         Online: Event RSVP

RSVP Deadline: April 27, 2014

Winston-Salem, NC

Date: Thursday, May 1, 2014

Program: On-Demand Treatment Plan for Sudden Attacks of HAE: Services and Options

Time: 6:30pm

Speaker: Maeve E. O'Connor, MD; Allergy, Asthma & Immunology Relief of Charlotte

Venue: Milner's American Southern directions

Address: 630 S Stratford Road

            Winston-Salem, NC 27103

Meeting Detail: Complimentary dinner event

RSVP: Phone: 704-576-4524 Julie Yencer
         Online: Event RSVP

RSVP Deadline: April 29, 2014

Cullman, AL

Date: Friday, May 2, 2014

Program: On-Demand Treatment Plan for Sudden Attacks of HAE: Services and Options

Time: 6:30pm

Speaker: Michael E. Manning, MD; Allergy, Asthma & Immunology Associates, Ltd

Venue: Top of the Town directions

Address: 316 2nd Avenue SW (HWY 31)

            4th Floor

            Cullman, AL 35055

Meeting Detail: Complimentary dinner event

RSVP: Phone: 617-763-3650 Deneen Newman 
         Online: Event RSVP

RSVP Deadline: April 30, 2014

Minnetonka, MN

Date: Thursday, May 15, 2014

Program: On-Demand Treatment Plan for Sudden Attacks of HAE: Services and Options

Time: 6:30pm

Speaker: Michael E. Manning, MD; Allergy, Asthma & Immunology Associates, Ltd

Venue: BLVD Kitchen & Bar directions

Address: 11544 Wayzata Boulevard

            Minnetonka, MN 55305

Meeting Detail: Complimentary dinner event

RSVP: Phone: 617-909-7046 Kelly Sparacino
         Online: Event RSVP

RSVP Deadline: May 13, 2014

San Antonio, TX

Date: Saturday, May 17, 2014

Program: On-Demand Treatment Plan for Sudden Attacks of HAE: Services and Options

Time: 12:00pm

Speaker: Ray Rodriguez, MD; Pediatric Allergy Immunology Service, University of Mississippi Medical Center

Venue: Paesanos 1604 directions

Address: 3622 Paesanos Parkway

            San Antonio, TX 78231

Meeting Detail: Complimentary lunch event

RSVP: Phone: 617-763-3650 Deneen Newman
         Online: Event RSVP

RSVP Deadline: May 15, 2014

Tulsa, OK

Date: Wednesday, May 21, 2014

Program: On-Demand Treatment Plan for Sudden Attacks of HAE: Services and Options

Time: 6:30pm

Speaker: Marc Riedl, MD, MS; Associate Professor of Medicine, Division of Rheumatology, Allergy & Immunology at University of California, San Diego

Venue: Polo Grill directions

Address: 2038 Utica Square

            Tulsa, OK 74114

Meeting Detail: Complimentary dinner event

RSVP: Phone: 617-894-2761 Eric Perry 
         Online: Event RSVP

RSVP Deadline: May 19, 2014

Winter Park, FL

Date: Saturday, June 7, 2014

Program: On-Demand Treatment Plan for Sudden Attacks of HAE: Services and Options

Time: 12:00pm

Speaker: Pragnesh Patel, MD; Allergy, Asthma Specialists of Central Florida

Venue: Mitchell's Fish Market directions

Address: 460 N. Orlando Avenue, Suite 122

            Winter Park, FL 32789

Meeting Detail: Complimentary lunch event

RSVP: Phone: 617-947-4067 Andrew Sternfield
         Online: Event RSVP

RSVP Deadline: June 5, 2014

Houma, LA

Date: Saturday, June 21, 2014

Program: On-Demand Treatment Plan for Sudden Attacks of HAE: Services and Options

Time: 1:00pm

Speaker: Mark Davis-Lorton, MD; Winthrop University Hospital

Venue: Big Al's Seafood Restaurant directions

Address: 1377 West Tunnel Boulevard

            Houma, LA 70360

Meeting Detail: Complimentary lunch event

RSVP: Phone: 617-763-3650 Deneen Newman
         Online: Event RSVP

RSVP Deadline: June 19, 2014

Boca Raton, FL

Date: Tuesday, September 16, 2014

Program: On-Demand Treatment Plan for Sudden Attacks of HAE: Services and Options

Time: 6:30pm

Speaker: Donald McNeil, MD; Optimed Infusion and Research LLC; Midwest Allergy and Asthma Associates; Worthington, OH

Venue: The Capital Grille directions

Address: 6000 Glades Road

            Boca Raton, FL 33431

Meeting Detail: Complimentary dinner event

RSVP: Phone: 617-947-4067 Andrew Sternfield
         Online: Event RSVP

RSVP Deadline: September, 14, 2014

Jacksonville, FL

Date: Wednesday, October 22, 2014

Program: On-Demand Treatment Plan for Sudden Attacks of HAE: Services and Options

Time: 6:30pm

Speaker: Robert Chrzanowski, MD; The Allergy Center at Brookstone

Venue: Mitchell's Fish Market directions

Address: 5205 Big Island Drive

            Jacksonville, FL 32246

Meeting Detail: Complimentary dinner event

RSVP: Phone: 617-947-4067 Andrew Sternfield
         Online: Event RSVP

RSVP Deadline: October 20, 2014

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Important Safety
Information for KALBITOR.

 safety information

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Read stories from real HAE patients about their experiences with KALBITOR.

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KALBITOR is a prescription medicine used to treat sudden attacks of hereditary angioedema (HAE) in people 12 years of age and older. KALBITOR is not a cure for HAE.
EXPAND 
Important Safety Information

KALBITOR® (ecallantide) for subcutaneous use should only be given by a doctor or nurse with appropriate medical support to treat serious allergic reactions and your hereditary angioedema. You should read the Medication Guide before you start receiving KALBITOR and before each treatment.

Serious allergic reactions may happen in some people who receive KALBITOR. These allergic reactions can be life-threatening and usually happen within 1 hour after receiving KALBITOR.

Symptoms of a serious allergic reaction to KALBITOR can be similar to the symptoms of hereditary angioedema, the condition that you are being treated for. Your doctor or nurse should watch you for any signs of a serious allergic reaction after treatment with KALBITOR. Tell your doctor or nurse right away if you have any of these symptoms of a serious allergic reaction during or after treatment with KALBITOR:

  • wheezing, shortness of breath, cough, chest tightness, or trouble breathing
  • dizziness, fainting, fast or weak heartbeat, or feeling nervous
  • reddening of the face, itching, hives, or feeling warm
  • swelling of the throat or tongue, throat tightness, hoarse voice, or trouble swallowing
  • runny nose, nasal congestion or sneezing

Do not receive KALBITOR if you are allergic to KALBITOR. Before receiving KALBITOR, tell your doctor if you have ever had an allergic reaction to KALBITOR.

Before receiving KALBITOR, tell your doctor about all of your health conditions, including any allergies you may have, whether you are pregnant, plan to become pregnant, or are breast feeding or plan to breast feed. It is not known if KALBITOR will harm your unborn baby or if KALBITOR passes into your breast milk. Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

Common side effects of KALBITOR include headache, nausea, diarrhea, fever, injection site reactions, such as redness, rash, swelling, itching, or bruising, and stuffy nose.

Talk to your doctor for more information and if you have any questions about your treatment.

Please see the Full Prescribing Information, including Boxed Warning and Medication Guide.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.