Talk to your Doctor | KALBITOR® (ecallantide)

Talk to Your Doctor to Be Prepared

Living with hereditary angioedema can be very hard. Currently there is no known cure. But it's important to know that treatments are available. Work together with your doctor to find an HAE treatment that's right for you.

Download a "Doctor Discussion Guide". Fill it out and bring it to the next appointment with your doctor; it may help guide your discussion in choosing an HAE treatment option best suited for you.

Many people with HAE take medicine on a regular basis to help prevent attacks. Even with preventive treatment, attacks can happen anyway. When they do, acute treatment is available.

If you think you have HAE, you may want to ask your doctor:

How is HAE diagnosed?
Can HAE be mistaken for other conditions?
Could I have inherited HAE from my parents?
How is HAE managed?

If you have been diagnosed with HAE, you may want to ask your doctor:

What treatments can you prescribe for HAE?
What are the side effects of these treatments?
How effective are these treatments?
What should I do if an HAE attack affects my breathing?
If I'm going to travel, what plans should I make?
How can I tell if I am likely to pass HAE on to my children?
Am I a candidate for acute or preventive treatment?

Ask your doctor if KALBITOR is right for you. Read some common questions about KALBITOR.

Important Safety Information

KALBITOR^® (ecallantide) for subcutaneous use should only be given by a doctor or nurse with appropriate medical support to treat serious allergic reactions and your hereditary angioedema. You should read the Medication Guide before you start receiving KALBITOR and before each treatment.

Serious allergic reactions may happen in some people who receive KALBITOR. These allergic reactions can be life-threatening and usually happen within 1 hour after receiving KALBITOR.

Symptoms of a serious allergic reaction to KALBITOR can be similar to the symptoms of hereditary angioedema, the condition that you are being treated for. Your doctor or nurse should watch you for any signs of a serious allergic reaction after treatment with KALBITOR. Tell your doctor or nurse right away if you have any of these symptoms of a serious allergic reaction during or after treatment with KALBITOR:

wheezing, shortness of breath, cough, chest tightness, or trouble breathing
dizziness, fainting, fast or weak heartbeat, or feeling nervous
reddening of the face, itching, hives, or feeling warm
swelling of the throat or tongue, throat tightness, hoarse voice, or trouble swallowing
runny nose or sneezing

Do not receive KALBITOR if you are allergic to KALBITOR. Before receiving KALBITOR, tell your doctor if you have ever had an allergic reaction to KALBITOR.

Before receiving KALBITOR, tell your doctor about all of your health conditions, including any allergies you may have, whether you are pregnant, plan to become pregnant, or are breast feeding or plan to breast feed. It is not known if KALBITOR will harm your unborn baby or if KALBITOR passes into your breast milk.

Common side effects of KALBITOR include headache, nausea, diarrhea, fever, injection site reactions, such as redness, rash, swelling, itching, or bruising, and stuffy nose.

Talk to your doctor for more information and if you have any questions about your treatment.

Please see Full Prescribing Information, including Boxed Warning and Medication Guide.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

kalbitor ecallantide

Talk to Your Doctor to Be Prepared

Important Safety Information