Acute attacks
Sudden attacks of hereditary angioedema.
Clinical trials
Studies that evaluate the effectiveness and safety of medications or medical devices before they are approved for use by the general public.
Ecallantide (e-KAL-lan-tide)
A protein made in yeast cells; ecallantide is the active ingredient in KALBITOR (ecallantide).
Abbreviation for hereditary angioedema.
Hereditary Angioedema
A rare, hereditary disease of the immune system that causes attacks of sudden swelling in various parts of the body.
KALBITOR Home Infusion Services®
KALBITOR Home Infusion Services is a program in which an experienced infusion nurse will administer your subcutaneous KALBITOR treatment in the comfort of your own home. This professional service is available to HAE patients, 12 years of age or older, who use KALBITOR to treat their sudden HAE attacks on demand. KALBITOR Home Infusion Services is not appropriate for treating laryngeal attacks.
KALBITOR® (KAL-bit-or)
A prescription medicine used to treat sudden attacks of hereditary angioedema in patients 12 years of age and older. KALBITOR® is not a cure for HAE.
Laryngeal attack
An HAE attack that affects the larynx (throat); this can block or close the airway, leading to difficulty breathing and, potentially, death.
The part of the throat that contains the vocal cords and is used for breathing, swallowing, and talking.
On-demand treatment
On-demand HAE treatment is used to treat sudden attacks of HAE as they occur, in order to relieve symptoms associated with the attack. On-demand treatment is not used to prevent attacks from occurring.
Plasma kallikrein (kal'i-kre'in)
A protein in the body that triggers the release of a substance that may lead to hereditary angioedema attack symptoms.
Under the skin.
In hereditary angioedema, something that causes an attack.
Please note:

The web site you are about to visit is neither owned nor controlled by Dyax Corp. Dyax is not responsible for the content, products or services on this site.

Do you wish to continue?

Please note:

You are about to leave the KALBITOR website to visit another
site that contains Dyax-managed content.

Do you wish to continue?

Don't Go it Alone

With KALBITOR® (ecallantide) treatment, you can always count on KALBITOR Care® personalized patient support services, available to you 24 hours a day, 7 days a week, delivered to you by the experienced staff at KALBITOR Access®.

Please see Full Prescribing Information, including Boxed Warning and Medication Guide.

Getting Started with KALBITOR Access®

Once you and your doctor have decided that KALBITOR® (ecallantide) is the right option for treating your hereditary angioedema (HAE) attacks, follow these two easy steps to enroll in KALBITOR Access and begin receiving resources and support.

Step 1

Review and complete the KALBITOR Access Patient Authorization Form (also available through your provider).

Step 2

FAX the completed form to KALBITOR Access at 1-888-806-4829.
CALL KALBITOR Access at 1-888-4KALBITOR (1-888-452-5248) for details on completing through electronic signature.

Customized Care to Assist You with Your Treatment

Once your form is received, your assigned treatment coordinator will:

  • Coordinate with your healthcare provider for KALBITOR prescription
  • Verify where you plan to receive KALBITOR treatment
  • Schedule an in-person visit from one of our Field Nurse Case Managers at your home, doctor's office, or other location of your choice to discuss your KALBITOR treatment
  • Begin your customized health insurance benefits review and financial assistance evaluation
  • Coordinate KALBITOR shipments to your home
  • Answer your questions about receiving KALBITOR treatment

Enrolling in KALBITOR Home Infusion Services®

The first step to signing up for KALBITOR Home Infusion Services is speaking with your doctor. KALBITOR is available only by prescription, and KALBITOR Home Infusion Services represents just one of several treatment options.

If you and your doctor determine that KALBITOR Home Infusion Services is right for you:

  • Your doctor will enroll you by submitting the KALBITOR Home Infusion Services Form
  • If approved, you can receive a free consultation visit, in which a home infusion nurse will explain the process and answer your questions.

KALBITOR Home Infusion Services are administered by a third party infusion services provider. Dyax Corp. does not provide these services.  Home Infusion Services may not be appropriate for all patients and is not appropriate for treatment of laryngeal attacks. KALBITOR is not indicated for self-administration and should only be given with appropriate medical support to treat serious allergic reactions and your HAE.

Once your treatment plan is in place, KALBITOR Access can continue to be a great resource for you, so stay in touch. To learn more about what KALBITOR Access might be able to do for you, please contact our team of service representatives toll-free at 1-888-4KALBITOR (1-888-452-5248), 24 hours a day, 7 days a week.

Print Page |

Please make sure to read
Important Safety
Information for KALBITOR.

safety information

Join the community to receive the latest updates about KALBITOR, patient services, and local events.

sign up now

Interested in speaking with a KALBITOR Access specialist about patient services? You can request a callback at a time convenient for you.

request a call
KALBITOR is a prescription medicine used to treat sudden attacks of hereditary angioedema (HAE) in people 12 years of age and older. KALBITOR is not a cure for HAE.
Important Safety Information

KALBITOR® (ecallantide) for subcutaneous use should only be given by a doctor or nurse with appropriate medical support to treat serious allergic reactions and your hereditary angioedema. You should read the Medication Guide before you start receiving KALBITOR and before each treatment.

Serious allergic reactions may happen in some people who receive KALBITOR. These allergic reactions can be life-threatening and usually happen within 1 hour after receiving KALBITOR.

Symptoms of a serious allergic reaction to KALBITOR can be similar to the symptoms of hereditary angioedema, the condition that you are being treated for. Your doctor or nurse should watch you for any signs of a serious allergic reaction after treatment with KALBITOR. Tell your doctor or nurse right away if you have any of these symptoms of a serious allergic reaction during or after treatment with KALBITOR:

  • wheezing, shortness of breath, cough, chest tightness, or trouble breathing
  • dizziness, fainting, fast or weak heartbeat, or feeling nervous
  • reddening of the face, itching, hives, or feeling warm
  • swelling of the throat or tongue, throat tightness, hoarse voice, or trouble swallowing
  • runny nose, nasal congestion or sneezing

Do not receive KALBITOR if you are allergic to KALBITOR. Before receiving KALBITOR, tell your doctor if you have ever had an allergic reaction to KALBITOR.

Before receiving KALBITOR, tell your doctor about all of your health conditions, including any allergies you may have, whether you are pregnant, plan to become pregnant, or are breast feeding or plan to breast feed. It is not known if KALBITOR will harm your unborn baby or if KALBITOR passes into your breast milk. Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

Common side effects of KALBITOR include headache, nausea, diarrhea, fever, injection site reactions, such as redness, rash, swelling, itching, or bruising, and stuffy nose.

Talk to your doctor for more information and if you have any questions about your treatment.

Please see the Full Prescribing Information, including Boxed Warning and Medication Guide.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.