HAE Resources
The following websites can provide more information on hereditary angioedema (HAE).
(Please note: By clicking any of the links below, you will leave KALBITOR.com.)
HAE Hope – An informational website about Hereditary Angioedema sponsored by Dyax Corp.
US Hereditary Angioedema Association – A nonprofit organization offering HAE information and forums where you can connect with other patients
National Organization for Rare Disorders (NORD) – An organization that focuses on the issues faced by people who are living with a rare disease
Food and Drug Administration (FDA) – Find information on clinical trials and new drug approvals
Patient Services Incorporated (PSI) - A non-profit, charitable organization. PSI is a premium and co-payment assistance foundation for the chronically ill
Sources used to write this site include:
Agostoni A, Aygoren-Pursun E, Binkley KE, et al. Hereditary and acquired angioedema: Problems and progress: Proceedings of the third C1 esterase inhibitor deficiency workshop and beyond. J Allergy Clin Immunol. 2004;114(3 Suppl): S51-131.
Agostoni A, Cicardi M. Hereditary and acquired C1-inhibitor deficiency: biological and clinical characteristics in 235 patients. Med. 1992;71:206-215.
Bork K, Fischer B, Dewald G. Recurrent Episodes of Skin Angioedema and Severe Attacks of Abdominal Pain Induced by Oral Contraceptives or Hormone Replacement Therapy. Am J Med 2003; 114:294-8.
Bork K, Meng G, Staubach P, Hardt J. Hereditary angioedema: new findings concerning symptoms, affected organs, and course. Am J Med. 2006;119:267-274.
Bowen T, Cicardi M, Bork K, et al. Hereditary angioedema: a current state-of-the-art review, VII: Canadian Hungarian 2007 international consensus algorithm for the diagnosis, therapy, and management of hereditary angioedema. Ann Allergy Asthma Immunol. 2008;100:S30-S40.
Davis A. Hereditary angioedema: a current state-of-the-art review, III: mechanisms of hereditary angioedema. Ann Allergy Asthma Immunol. 2008;100:S7-S12.
Genetics Home Reference/US National Library of Medicine. Available at: http://ghr.nlm.nih.gov/condition=hereditaryangioedema. Accessed April 7, 2010.
Gompels M, Lock R, Abinum M, et al. C1 inhibitor deficiency: consensus document. Clin and Exp Immunol. 2005;139:379-394.
Joseph K, Tuscano TB, Kaplan AP. Studies of the mechanisms of bradykinin generation in hereditary angioedema plasma. Ann Allergy Asthma Immunol. 2008;101:279-286.
KALBITOR® (ecallantide) Full Prescribing Information, Dyax Corp., Cambridge, Massachusetts, December 2009.
Kaplan AP, Joseph, K, Silverberg M. Pathways for bradykinin formation and inflammatory disease. J Allergy Clin Immunol. 2002;109:195-209.
Schneider L, Lumry W, Vegh A, Williams A, Schmalbach T. Critical role of kallikrein in hereditary angioedema pathogenesis: A clinical trial of ecallantide, a novel kallikrein inhibitor. J Allergy Clin Immunol. 2007;120:416-422.